Darwin Publications

Articles in peer-reviewed journals:

  1. Wiche, E. Briones, H. Hirt, R. Krepler, U. Artlieb and H. Denk (1983). Differential distribution of microtubule-associated proteins MAP- 1 and MAP-2 in neurons of rat brain and association of MAP-1 with microtubules of neuroblastoma cells (N2A). EMBO J. 2, 11, 915-919.

  2. Hirt, J. Kimelman, M. Birnbaum, E. Chen, P. Seeburg, N.  Eberhardt and A. Barta (1987). The human growth hormone gene locus: structure, evolution and  allelic variants. DNA, 6, 59-65.

  3. Hirt, G. Casari and A. Barta (1989). Cadmium-enhanced gene expression in suspension culture cells of tobacco. Planta 179, 414-420.

  4. Hirt, K. Sommergruber and A. Barta (1990). Effects of Cadmium on Tobacco:  Synthesis and Regulation of Cadmium-Binding Peptides. Biochem. Physiol. Pflanzen 186, 153-163.

  5. Hirt, M. Kögl, T. Murbacher and E. Heberle-Bors (1990). Evolutionary conservation of transcription machinery between yeast and plants as shown by the efficient expression from the CaMV 35S promoter and 35S terminator. Curr. Genet. 17, 473-479.

  6. Hirt, A. Pay, J. Györgyey, L. Bako, L. Bögre, R. Schweyen, E. Heberle-Bors and D. Dudits (1991). Complementation of yeast cell cycle mutant by alfalfa cDNA encoding a protein kinase homolog of the p34cdc2. Proc. Natl. Acad. Sci. 88, 1636-1640.

  7. Györgyey, A. Gartner, K. Nemeth, Z. Magyar, H. Hirt, E. Heberle-Bors and D. Dudits (1991). Alfalfa heat shock genes are differentially expressed during somatic embryogenesis. Plant Mol. Biol. 16, 999-1007.

  8. Pay, E. Heberle-Bors and H. Hirt (1991). Isolation and characterization of the plant homologue of the eukaryotic initiation factor 4D from alfalfa, Medicago sativa. Plant Mol. Biol. 17, 927-929.

  9. Hirt (1991) A novel method for in situ screening of yeast colonies with the ß-glucuronidase reporter gene. Curr. Genet. 20, 437-439.

  10. Hirt, A. Gartner and E. Heberle-Bors (1992). An alfalfa cDNA encodes a protein with similarity to mammalian snRNP-E proteins. Nucl. Acids Res. 20, 613.

  11. Pay, E. Heberle-Bors and H. Hirt (1992) An alfalfa cDNA encodes a protein with similarity to human translationally controlled tumor protein. Plant Mol. Biol. 19, 501-503.

  12. Rüth, H. Hirt and R. Schweyen (1992). The 35S Cauliflower Mosaic Virus Promoter is regulated by cAMP in Saccharomyces cerevisiae. Mol. Gen. Genet. 235, 365-372.

  13. Pay, C. Jonak, L. Bögre, I. Meskiene, E. Heberle-Bors and H. Hirt (1993). The MsK family of alfalfa protein kinase genes encodes homologs of shaggy/glycogen synthase kinase-3 and shows differential expression patterns in plant organs and development. Plant J. 3, 847-856.

  14. Pirck, A. Pay, L. Bögre, E. Heberle-Bors and H. Hirt (1993). Isolation and characterization of phosphoprotein phosphatase type 2a from alfalfa. Mol. Gen. Genet. 240, 126-131.

  15. Hirt, M. Mink, M. Pfosser, L. Bögre, J. Györgyey, C. Jonak, A. Gartner, D. Dudits and E. Heberle-Bors (1992). Alfalfa cyclins: differential expression during the cell cycle and in planta. Plant Cell 4, 1531-1538.

  16. Jonak, A. Pay, L. Bögre, H. Hirt and E. Heberle-Bors (1993). The plant homologue of MAP kinase is expressed in a cell cycle-dependent and organ-specific manner. Plant J. 3, 611-617.

  17. Hirt, A. Pay, L. Bögre, I. Meskiene and E. Heberle-Bors (1993). cdc2MsB, a cognate cdc2 gene from alfalfa, complements the G1/S but not the G2/M transition of budding yeast cdc28 mutants. Plant J. 4, 61-69.

  18. Pirck, H. Hirt, and E. Heberle-Bors (1994). The cDNA sequence encoding an annexin from Medicago sativa. Plant Phys. 104, 1463-1464.

  19. Rüth, R.J. Schweyen, and H. Hirt (1994). The plant transcription factor TGA1 stimulates expression of the CaMV 35S promoter in Saccharomyces cerevisiae. Plant Mol. Biol. 25, 323-328.

  20. Jonak, E. Heberle-Bors, and H. Hirt (1994). MAP kinases: universal multi-purpose signaling tools. Plant Mol. Biol. 24, 407-416.

  21. Hirt, and E. Heberle-Bors (1994). Cell cycle regulation in higher plants. Sem. Dev. Biol. 5, 147-154.

  22. Pay, M. Pirck, L. Bögre, H. Hirt, and E. Heberle-Bors (1994). Isolation and characterization of phophoprotein phosphatase 1 from alfalfa. Mol. Gen. Genet. 244, 176-182.

  23. Yang, C. de Blank, I. Meskiene, H. Hirt, J. Bakker, A. van Kammen, H. Franssen, and T. Bisseling (1994). Rhizobium Nod factors reactivate the cell cycle during infection and nodule formation, but the cycle is only completed in primordium formation. Plant Cell 6, 1415-1426.

  24. Jonak, E. Heberle-Bors, and H. Hirt (1995). A cDNA from Medicago sativa encodes a protein homologous to small GTP-binding proteins. Plant Phys. 107, 263-264.

  25. Jonak, E. Heberle-Bors, and H. Hirt (1995). Inflorescence-specific expression of AtK-1, a novel Arabidopsis thaliana homologue of shaggy/glycogen synthase kinase-3. Plant Mol. Biol. 27, 217-221.

  26. Magdolen, H. Klier, T. Wöhl, F. Klink, H. Hirt, J. Hauber, and F. Lottspeich. (1995). The function of the hypusine-containing proteins of yeast and other eukaryotes is well conserved. Mol. Gen. Genet. 244, 646-652.

  27. Jonak, S. Kiegerl, C. Lloyd, J. Chan, and H. Hirt (1995). MMK2, a novel alfalfa MAP kinase, specifically complements the yeast MPK1 function. Mol. Gen. Genet. 248, 686-694.

  28. Meskiene, L. Bögre, M. Dahl, M. Pirck, D.T.C. Ha, I. Swoboda, E. Heberle-Bors, G. Ammerer, and H. Hirt (1995). cycMs3, a novel B-type alfalfa cyclin gene, is induced in the G0-to-G1 transition of the cell cycle. Plant Cell 7, 759-771.

  29. Haring, M. Siderius, C. Jonak, H. Hirt, K. Walton, and A. Musgrave (1995). Tyrosine phosphatase signalling in a lower plant: cell cycle and oxidative stress-regulated expression of the Chlamydomonas eugametos VH-PTP13 gene. Plant J. 7, 981-988.

  30. Dahl, I. Meskiene, L. Bögre, D.T.C. Ha, I. Swoboda, R. Hubmann, H. Hirt, and E. Heberle-Bors (1995). The D-type alfalfa cyclin gene cycMs4 complements G1 cyclin deficient yeast and is induced in the G1 phase of the cell cycle. Plant Cell, 1847-1859. 

  31. Bögre, C. Jonak, M. Mink, I. Meskiene, J. Traas, D.T.C. Ha, I. Swoboda, C. Plank, E. Wagner, E. Heberle-Bors, and H. Hirt (1996). Developmental and cell cycle regulation of alfalfa nucMs1, a plant homolog of the yeast Nsr1 and mammalian nucleolin. Plant Cell 8, 417-428.

  32. Jonak, S. Kiegerl, W. Ligterink, P. J. Barker, N.S. Huskisson, and H. Hirt (1996). Stress signalling in plants: A MAP kinase pathway is activated by cold and drought. Proc. natl. Acad. Sci. USA 93, 11274-11279.

  33. Renaudin, J.H. Doonan, D. Freeman, J. Hashimoto, H. Hirt, D. Inze, T. Jacobs, H. Kouchi, P. Rouze, M. Sauter, A. Savoure, D.A. Sorrell, V. Sundaresan, And J.A.H. Murray (1996). A unified nomenclature for plant A-, B-, and D-type cyclins based on sequence organisation. Plant Mol. Biol. 32, 1003-1018.

  34. Bögre, W. Ligterink, E. Heberle-Bors, and H. Hirt (1996) Mechanosensors in plants. Nature 383, 489-490.

  35. Hirt (1996). In and out of the plant cell cycle. Plant Mol. Biol. 31, 459-464.

  36. Hirt (1997) Multiple roles of MAP kinases in plant signal transduction. Trends Plant Sci. 2, 11-15

  37. Bögre, W.  Ligterink, I. Meskiene, P. J. Barker, E. Heberle-Bors, N.S. Huskisson, and H. Hirt (1997) Wounding induces the rapid and transient activation of a specific MAP kinase pathway. Plant Cell 9, 75-83.

  38. Bögre, K. Zwerger, I. Meskiene, P. Binarova, V. Csizmadia, C. Planck, E. Wagner, H. Hirt, and E. Heberle-Bors (1997) The cdc2Ms kinase is differently regulated in the cytoplasm and in the nucleus. Plant Physiol. 113, 841-852.

  39. Ligterink, T. Kroj, U. zur Nieden, H.. Hirt, and D. Scheel (1997) Receptor-mediated activation of a MAP kinase in pathogen defense of plants. Science 276, 2054-2057. 

  40. Meskiene, L. Bögre, W. Glaser, J. Balog, M. Brandstötter, K. Zwerger, G. Ammerer, and H. Hirt (1998) MP2C, a protein phosphatase 2C, is a negative regulator of the stress-activated MAP kinase pathway in plants. Proc. Natl. Acad. Sci. USA 95, 1938-1943.

  41. Wilson, M. Pfosser, C. Jonak, H. Hirt, E. Heberle-Bors, and O. Vicente (1998) Evidence for the activation of a MAP kinase upon phosphate-induced cell cycle re-entry in tobacco cells. Phys. Plant. 102, 532-538

  42. Meskiene, W. Ligterink, L. Bögre, C. Jonak, S. Kiegerl, J. Balog, S. Eklöf, G. Ammerer, and H. Hirt (1998) The SAM kinase pathway: An integrated circuit for stress signaling in plants. J. Plant Res. 111, 339-344.

  43. Jonak, C., Ligterink, W., and H. Hirt (1999) MAP kinases as transducers in plant signalling. Cell. Mol. Life Sci. 55, 204-213.

  44.  Hirt, H. (1999) Transcriptional upregulation of signaling pathways: more complex than anticipated? Trends Plant Sci. 4, 7-8

  45.  Cardinale, F. Ligterink, W., Baudouin, E., Beyerly, J., Hausl, C., Jonak, C., Kiegerl, S., Meskiene, I., Siligan, C., Zwerger, K., and Hirt, H. (1999) MAP kinase activation in plant defense. Biologia 54, 56-57.

  46. Bögre, L., Calderini, O., Binarova, P., Mattauch, M., Till, S., Kiegerl, S., Jonak, C., Pollaschek, C., Barker, P., Huskisson, N.V., Hirt, H., and Heberle-Bors, E. (1999) A MAP kinase is activated late in plant mitosis and becomes localized to the plane of cell division. Plant Cell 11, 101-113.

  47.  Romeis, T., Piedras, P., Zhang, S., Klessig, D., Hirt, H., Jones, J.D.G. (1999) Rapid Avr-9 and Cf-9-dependent activation of MAP kinases in tobacco cell cultures and leaves: convergence of resistance gene, elicitor, wound, and salicylate responses. Plant Cell 11, 273-287.

  48.  Munnik, T., Ligterink, W., Meskiene, I., Calderini, O., Musgrave, A., and Hirt, H. (1999) Distinct osmosensing protein kinase pathways are involved in signaling moderate and severe hyperosmotic stress. Plant J. 20, 381-388.

  49.  Baudouin, E., Meskiene, I., and Hirt, H. (1999) Unsaturated fatty acids inhibit MP2C, a protein phosphatase 2C involved in the wound-induced MAP kinase pathway regulation. Plant J. 20, 1-6.  

  50.  Fujikura Y., Dolezel, J., Cihalikova, J., Bögre, L., Heberle-Bors, E. Hirt, H., and Binarova, P. (1999) Vicia faba germination: Synchronized cell growth and localisation of nucleolin and α-tubulin. Seed Sci. Res. 9, 297-304.

  51. Munnik, T., Meijer, H.J.G., ter Riet, B., Hirt, H., Frank, W., Bartels, D., and Musgrave, A. (2000) Hyperosmotic stress stimulates phospholipase D activity and elevates the levels of phosphatidic acid and diacylglycerol pyrophosphate. Plant J. 22, 147-154.

  52. Nühse, T.S., Peck, S.C., Hirt, H., and Boller, T. (2000) Microbial elicitors induce activation and dual phosphorylation of the Arabidopsis thaliana MAPK6. J. Biol. Chem. 275, 7521-7526.

  53.  Hirt, H. (2000) Connecting oxidative stress, auxin, and cell cycle regulation through a plant mitogen-activated protein kinase pathway. Proc. Natl. Acad. Sci. USA 97, 2405-2407.

  54.  Jonak, C., Beisteiner, D., Beyerly, J., and Hirt, H. (2000) Wound-induced expression and activation of WIG, a novel glycogen synthase kinase 3. Plant Cell 12, 1467-1475.

  55.  Baluska, F., Ovecka, M., and Hirt, H. (2000) Salt stress induces changes in amounts and localisation of the mitogen-activated protein kinase SIMK in alfalfa roots. Protoplasma 212, 262-267.

  56. Fellbrich, G., Blume, B., Brunner, F., Hirt, H., Kroj, T., Ligterink, W., Romanski, A., and Nürnberger, T. (2000) Phytophthora parasitica elicitor-induced reactions in cells of Petroselinum crispum. Plant Cell Physiol. 41, 692-701.

  57.  Kiegerl, S., Cardinale, F., Siligan, C., Gross, A., Liwosz, A., Eklöf, S., Till, S., Bögre, L., Hirt, H. and Meskiene, I. (2000) SIMKK, a mitogen-activated protein kinase (MAPK) kinase, is a specific activator of the salt stress-induced MAPK SIMK. Plant Cell 12, 2247-2258.

  58. Cardinale, F. Jonak, C., Ligterink, W., Niehaus, K., Boller, T., and Hirt, H. (2000) Differential activation of four specific MAPK pathways by distinct elicitors. J. Biol. Chem. 275, 36734-36740.

  59. Bögre, L., Meskiene, I., Heberle-Bors, E., and Hirt, H. (2000) Stressing the role of MAP kinases in mitogenic stimulation. Plant Mol. Biol. 43, 705-718.

  60. Meskiene, I. and Hirt, H. (2000) MAP kinase pathways: molecular plug-and-play chips for the cell. Plant Mol. Biol. 42, 791-806.

  61. Ligterink, W., and Hirt, H. (2001) MAP kinase pathways in plants: versatile signaling tools. Int. Rev. Cyt. 201, 209-275.

  62. Zwerger, K., and Hirt, H. (2001) Recent advances in plant MAP kinase signalling. Biol. Chem. 382, 1123-1131.

  63. Wrzaczek, M., and Hirt. H. (2001) Plant MAP kinase pathways: how many and what for? Biol. Cell 93, 81-87.

  64. Lee, S., Hirt, H., and Lee, Y. (2001) Phosphatidic acid activates a wound-activated SIMK-like MAP kinase in Glycine max. Plant J. 26, 479-486.

  65. Cardinale, F., Meskiene, I., Ouaked, F., and Hirt, H. (2002) Convergence and divergence of stress-induced MAPK signaling pathways at the level of two distinct MAP kinase kinases. Plant Cell 14, 703-711.

  66. Samaj, J., Ovecka, M., Hlavacka, A., Ouaked, F., Meskiene, I., Salaj, J., Lichtscheidl, I., Volkmann, D., Bögre, L., Baluska, F., Hirt, H. (2002) Involvement of the mitogen-activated protein kinase SIMK in regulation of root hair tip-growth. EMBO J. 21, 3296-3306.

  67. Ichimura, K., Tena, G., Henry, Y., Zhang, S., Hirt, H., Ellis, B.E., Morris, P.C., Wilson, C., Champion, A., Innes, R.W., Sheen, J., Ecker, J., Scheel, D., Klessig, D., Machida, Y., Mundy, J., Ohashi, Y., Kreis, M., Heberle-Bors, E., Walker, J., Shinozaki, K. (2002) Mitogen-activated protein kinase cascades in plants: Nomenclature of Arabidopsis MAP kinases and MAP kinase kinases. Trends Plant Sci. 7, 301-308.

  68. Sangwan, V., Örvar, B. L., Beyerly, J., Hirt, H., Dhindsa, R.S. (2002) Opposite changes in membrane fluidity mimic cold and heat stress activation of distinct plant MAP kinase pathways. Plant J. 31, 629-638.

  69. Jonak, C. and Hirt, H. (2002) Glycogen synthase kinase 3/shaggy-like kinases in plants: an emerging family with novel functions. Trends Plant Sci.7, 457-461.

  70. Jonak, C. Ökresz, L., Bögre, L., Hirt, H. (2002) Complexity, cross talk and integration of plant MAP kinase signalling. Curr. Op. Plant Biol. 5, 415-424.

  71. Hirt, H. (2002) A new blueprint for plant pathogen resistance. Nature Biotechnol. 20, 450-451.

  72. Samaj, J., Ovecka, M., Hlavacka, A., Ouaked, F., Meskiene, I., Salaj, J., Lichtscheidl, I., Volkmann, D., Bögre, L., Baluska, F., Hirt, H. (2003) Involvement of MAP kinase SIMK and actin cytoskeleton in the regulation of root hair tip growth. Cell Biol. Int. 27, 257-259.

  73. Jonak, C. and Hirt, H. (2003) Protein phosphorylation and cellular information transfer: signalling by MAP kinase cascades. Chem. Monthly 134, 1481-1487.

  74. Ouaked, F., Rozhon, W., Lecourieux, D. Hirt, H. (2003) A MAPK pathway mediates ethylene signaling in plants. EMBO J. 22, 1282-1288. 

  75. Meskiene, I., Baudouin, E., Schweighofer, A., Liwosz, A., Jonak, C., Rodriguez, P.L., Jelinek, H., and Hirt, H. (2003) Stress-induced protein phosphatase 2C is a negative regulator of a mitogen-activated protein kinase. J. Biol. Chem. 278, 18945-18952.

  76. Rentel, M.C., Lecourieux, D., Ouaked, F., Usher, S.L., Petersen, L., Okamoto, H., Knight, H., Peck, S.C., Grierson, C.S., Hirt, H. and Knight, M.R. (2004) OXI1 kinase is necessary for oxidative burst-mediated signalling in Arabidopsis. Nature 427, 858-861. 

  77. Nakagami, H., Kiegerl, S. and Hirt H. (2004) OMTK1, a novel MAPKKK, channels oxidative stress signaling through direct MAPK binding. J. Biol. Chem 279, 26959-26966

  78. Teige, M., Scheikl, E., Eulgem, T., Doczi, R., Ichimura, K., Shinozaki, K., Dangl, J.L., and Hirt, H. (2004) The MKK2 pathway mediates cold and salt stress signaling in Arabdiopsis. Mol. Cell 15, 141-152.

  79. Jonak, C., Nakagami, H., and Hirt, H. (2004) Molecular response to heavy metal stress: activation of distinct mitogen-activated protein kinase pathways by copper and cadmium. Plant Phys.136, 3276-3283.

  80. Samaj, J., Baluska, F., and Hirt, H. (2004) From signal to cell polarity: mitogen-activated protein kinases as sensors and effectors of cytoskeleton dynamics. J. Exp. Bot. 55, 189-98.

  81. Schweighofer, A., Hirt, H. and Meskiene, I. (2004) Plant PP2C Phosphatases: Emerging Functions. Trends Plant Sci. 9, 236-245.

  82. Apel, K. and Hirt, H. (2004) Reactive Oxygen Species: Metabolism, oxidative stress and signal transduction. Annu. Rev. Plant Biol. 55, 373-399.

  83. Nakagami, H., Pitzschke, A. Hirt, H. (2005) Emerging MAP kinase pathways in plant stress signalling.
    Trends Plant Sci.7, 339-46.

  84. Andreasson E, Jenkins T, Brodersen P, Thorgrimsen S, Petersen NH, Zhu S, Qiu JL, Micheelsen P, Rocher A, Petersen M, Newman MA, Bjorn Nielsen H, Hirt H, Somssich I, Mattsson O, Mundy J. (2005) The MAP kinase substrate MKS1 is a regulator of plant defense responses. EMBO J. 14 , 2579-89.

  85. de la Fuente van Bentem, S. Roitinger, E., Anrather, D., Csaszar, E. and Hirt, H. (2006) Phosphoproteomics as a tool to unravel plant regulatory mechanisms. Physiol. Plant. 126, 110-119.

  86. Veronese, P., Nakagami, H., Bluhm, B., AbuQamar, S., Chen, X., Salmeron, J., Dietrich, R.A., Hirt, H. and Mengiste T. (2006) The Membrane-Anchored BOTRYTIS INDUCED KINASE1 Has Distinct Roles in Arabidopsis Resistance to Necrotrophic and Biotrophic Pathogens. Plant Cell 18, 257-73

  87. de la Fuente van Bentem, S., Anrather, D., Roitinger, E., Djamei, A., Hufnagl, T., Barta, A., Csaszar, E., Dohnal, I.,  Lecourieux D. and Hirt H. (2006) Phosphoproteomics reveals extensive in vivo phosphorylation of Arabidopsis proteins involved in RNA metabolism. Nucl. Acids Res. 34, 3267-78.

  88. Fernandez-Pascual M, Lucas MM, de Felipe MR, Bosca L, Hirt H, Golvano MP. (2006) Involvement of mitogen-activated protein kinases in the symbiosis Bradyrhizobium-Lupinus.J Exp Bot. 57, 2735-42. 

  89. Nakagami, H., Soukupova, H., Schikora, A., Zarsky, V. and Hirt, H. (2006) A mitogen-activated protein kinase kinase kinase mediates reactive oxygen species homeostasis in Arabidopsis. J. Biol. Chem. 28, 3267-78. 

  90. Pitzschke, A., Forzani, C. and Hirt, H. (2006) Reactive oxygen signalling in plants. Antioxidant and Redox Signalling  , 1757-64.

  91.   Pitzschke, A and Hirt, H. (2006) MAPK-mediated reactive oxygen signalling in plants. Plant Phys. 141, 351-6.

  92.   van Bentem, S. and Hirt, H (2007) Using phosphoproteomics to reveal signalling dynamics in plants. Trends Plant Sci. 12, 404-409

  93. Daxberger, A., Nemak, A., Mithöfer, A., Fliegmann, J., Ligterink, W., Hirt, H., Ebel, J. (2007) Activation of members of a MAPK module in ß-glucan elicitor-mediated non-host resistance of soybean. Planta 6, 1559-71. 

  94. Kempa S, Rozhon W, Samaj J, Erban A, Baluska F, Becker T, Haselmayer J, Schleiff E, Kopka J, Hirt H, Jonak C. (2007) A plastid-localized glycogen synthase kinase 3 modulates stress tolerance and carbohydrate metabolism.
    Plant J. 49,1076-1090.

  95. Brader, G., Djamei, A., Teige, M., Palva, T. Hirt, H. (2007) The MAP kinase kinase MKK2 affects diseasse resistance in Arabidopsis. Mol. Plant Micr. Int. 20, 589-596.

  96. Schweighofer, A., Kazanaviciute, V., Scheikl, E., Teige, M., Doczi, R., Hirt, H., Schwanninger, M., Kant, M., Schuurink, R., Mauch, F., Buchala, A., Cardinale, F., and Meskiene I. (2007) The PP2C-Type Phosphatase AP2C1 Negatively Regulates MPK4 and MPK6 and Modulates Innate Immunity and Jasmonic Acid and Ethylene Levels in Arabidopsis. Plant Cell 7, 2213-24.  

  97. Kemmerling, B., Schwedt, A., Rodriguez, P., Mazzotta, S., Frank, M., Abu Qamar, S., Mengiste, T., Betsuyaku, S.,  Parker, J.E., Müssig, K., Thomma, B.P.H.J., Albrecht, C., de Vries, S., Hirt, H., and Nürnberger T. (2007)  The BRI1-Associated Kinase 1, BAK1, Has a Brassinolide-Independent Role in Plant Cell-Death Control. Current Biol. 17, 1116–1122

  98. Dóczi, R., Brader, G., Pettkó-Szandtner, A., Rajh, I., Djamei, A., Pitzschke, A., Teige, M., and Hirt, H. (2007) The Arabidopsis MAP Kinase Kinase MKK3 is Upstream of Group C MAP Kinases and Participates in Pathogen-Signaling. Plant Cell, 19, 3266-3279.

  99. Djamei, A., Pitzschke, A., Nakagami, H., Rajh, I., and Hirt, H. (2007) Trojan horse strategy in Agrobacterium transformation by abusing MAPK defence signalling. Science, 318, 453-456.

  100. de la Fuente van Bentem, S., Anrather, D., Dohnal, I., Roitinger, E., Csaszar, E., Joore, J., Buijnink, J., Carreri, A., Forzani, C., Lorkovic, Z., Barta, A., Lecourieux, D., Verhounig, A., Jonak, C., Hirt, H. (2008) Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis. J. Prot. Res. 7, 2458-2470.

  101. Schikora, A., Carreri, A., Charpentier, E., Hirt, H. (2008) The dark side of the salad : Salmonella typhimurium overcomes the innate immune response of Arabidiopsis thaliana and shows an endopathogenic lifestyle. PLOS One, 3:e2279.

  102. Chen PY, Lee KT, Chi WC, Hirt H, Chang CC, Huang HJ. (2008) Possible involvement of MAP kinase pathways in acquired metal-tolerance induced by heat in plants. Planta 228:499-509. 

  103. de la Fuente van Bentem S, Mentzen WI, de la Fuente A, Hirt H. (2008) Towards functional phosphoproteomics by mapping differential phosphorylation events in signaling networks. Proteomics 8:4453-4465. 

  104. Pieroni E, de la Fuente van Bentem S, Mancosu G, Capobianco E, Hirt H, de la Fuente A. (2008) Protein networking: insights into global functional organization of proteomes. Proteomics 4, 799-816. 

  105.  de la Fuente van Bentem, S., Mentzen, W., de la Fuente, A., and Hirt, H. (2008) Towards functional phosphoproteomics by mapping differential phosphorylation events in signalling networks. Proteomics 8:4453-4465.

  106. Colcombet, J., and Hirt, H (2008) Arabidopsis MAPK pathways: a complex signalling network involved in multiple biological processes. Biochem. J. 413:217-26.

  107. Pitzschke A, Hirt H (2009) Disentangling the complexity of mitogen-activated protein kinases and reactive oxygen species signaling. Plant Physiol. 149:606-15.

  108. Pitzschke A, Schikora A, Hirt H (2009) MAPK cascade signalling networks in plant defence. Curr Opin Plant Biol. 12:421-6.

  109. Van Bentem, S. and Hirt, H (2009) Tyrosine phosphorylation in plants: more abundant than expected? Trends Plant Sci.14:71-76.

  110. Pitzschke, A, Djamei, A, Bitton, F, Hirt, H (2009) A Major Role of the MEKK1–MKK1/2–MPK4 Pathway in ROS Signalling. Mol. Plant 2: 120-137.

  111. Pecinka, A., Rosa, M., Schikora, A., Berlinger, M., Hirt, H., Luschnig, C., Mitelsten-Scheid, O. (2009) Transgenereational stress memory is not a general response in Arabidopsis. PLOS One 4, e5502. 

  112. Pitzschke, A., Djamei, A., Teige, M., Hirt, H. (2009) VIP1 response elements mediate mitogen-activated protein kinase 3-induced stress gene expression. Proc. Natl. Acad. Sci. USA, 106:18414-9.

  113. Bartels, S., Anderson, J., Gonzalez Besteiro, M., Carreri, A., Hirt, H., Buchala, A., Metraux, J.-P., Peck, S., Ulm, R. (2009) MAP KINASE PHOSPHATASE1 and PROTEIN TYROSINE PHOSPHATASE1 Are Repressors of Salicylic Acid and SNC1-Mediated Responses in Arabidopsis. Plant Cell 9:2884-97.

  114. Pitzschke, A. and Hirt, H. (2009) Mechanism of MAPK-dependent transcriptional regulation uncovered. Cell Cycle 9: 18-9.

  115. Kosetsu K, Matsunaga S, Nakagami H, Colcombet J, Sasabe M, Soyano T, Takahashi Y, Hirt H, Machida Y. (2010) The MAP kinase MPK4 is required for cytokinesis in Arabidopsis thaliana. Plant Cell 22:3778-90.

  116. Pitzsche, A. and Hirt, H. (2010) Bioinformatic and systems biology tools to generate testable models of signaling pathways and their targets. Plant Phys. 152:460-9

  117. Pitzschke A, Hirt H.(2010) New insights into an old story: Agrobacterium-induced tumour formation in plants by plant transformation. EMBO J. 29:1021-32

  118. Forzani, C., Carreri, A., de la Fuente van Bentem, S., Lecourieux, D., Lecourieux, F., Hirt, H. (2011) The Arabidopsis protein kinase PTI1-4 is a common target of the oxidative signal-inducible1 (OXI1) and MAP kinases. FEBS J. 278:1126-36.  

  119. Pflieger D, Gonnet F, van Bentem S Hirt, H, de la Fuente A (2011) Linking the proteins – elucidation of proteome-scale networks using mass spectrometry. Mass Spectr. Rev. 30:268-97.

  120. Pflieger, D., Bigeard, J., Hirt, H. (2011) Isolation and characterization of protein complexes by mass spectrometry. Proteomics 9:1824-33.

  121. Camehl I, Drzewiecki C, Vadassery J, Shahollari B, Sherameti I, Forzani C, Munnik T, Hirt H, Oelmüller R. (2011) The OXI1 Kinase Pathway Mediates Piriformospora indica-Induced Growth Promotion in Arabidopsis. PLoS Pathog. 7:e1002051.

  122. Hirt, H. Garcia, A.V. and Oelmüller, R. (2011) AGC kinases in plant development and defense. Plant Sig. Behav. 6:7, 1-4.

  123. Schikora A, Virlogeux-Payant I, Bueso E, Garcia AV, Nilau T, Charrier A, Pelletier S, Menanteau P, Baccarini M, Velge P, Hirt H. (2011) Conservation of Salmonella infection mechanisms in plants and animals. PLoS One. 6:e24112.

  124. Samajová O, Plíhal O, Al-Yousif M, Hirt H, Samaj J. (2011) Improvement of stress tolerance in plants by genetic manipulation of mitogen-activated protein kinases. Biotechnol Adv. 

  125. Schikora M, Neupane B, Madhogaria S, Koch W, Cremers D, Hirt H, Kogel KH, Schikora A. (2012) An image classification approach to analyze the suppression of plant immunity by the human pathogen Salmonella Typhimurium. BMC Bioinformatics. 13:171. 

  126. Schikora A, Garcia AV, Hirt H. (2012) Plants as alternative hosts for Salmonella. Trends Plant Sci. 17:245-9. 

Garcia AV, Al-Yousif M, Hirt H. (2012) Role of AGC kinases in plant growth and stress responses. Cell Mol Life Sci. 69, :3259-67.

  1. Berriri S, Garcia AV, Frei Dit Frey N, Rozhon W, Pateyron S, Leonhardt N, Montillet JL, Leung J, Hirt H, Colcombet J. (2012) Constitutively Active Mitogen-Activated Protein Kinase Versions Reveal Functions of Arabidopsis MPK4 in Pathogen Defense Signaling. Plant Cell 24, :4281-93.

  2. Vandenbogaert M, Hourdel V, Jardin-Mathé O, Bigeard J, Bonhomme L, Legros V, Hirt H, Schwikowski B, Pflieger D. (2012) Automated phosphopeptide identification using multiple MS/MS fragmentation modes. J Proteome Res. 11, 5695-703.

  3. Colcombet J, Berriri S, Hirt H. (2012) Constitutively active MPK4 helps to clarify its role in plant immunity. Plant Signal Behav. 8, 

  4. Smeets K, Opdenakker K, Remans T, Forzani C, Hirt H, Vangronsveld J, Cuypers A.(2012) The role of the kinase OXI1 in cadmium and copper induced molecular responses in Arabidopsis thaliana. Plant Cell Environ. Dec 19

  5.  Hirt H (2012) Role of micro-organisms in adapting plants to environmental stress conditions. Biol Aujourdhui 206:285-90

  6. Latrasse D, Jégu T, Meng PH, Mazubert C, Hudik E, Delarue M, Charon C, Crespi M, Hirt H, Raynaud C, Bergounioux C, Benhamed M. (2013) Dual function of MIPS1 as a metabolic enzyme and transcriptional regulator. Nucleic Acids Res. 41(5):2907-17.

  7. Khan M, Rozhon W, Bigeard J, Pflieger D, Husar S, Pitzschke A, Teige M, Jonak C, Hirt H, Poppenberger B. (2013) Brassinosteroid-regulated GSK3/shaggy-like kinases phosphorylate MAP kinase kinases, which control stomata development in Arabidopsis thaliana.J Biol Chem. 288:7519-27. 

  8. Montillet, J.-L., Leonhardt, N., Mondy, S., Tranchimand, S., Rumeau, D., Boudsocq, M., Garcia, A.V., Douki, T., Bigeard, J., Laurière, C., Chevalier, A., Castresana, C., Hirt, H. (2013) An ABA-independent oxylipin pathway controls stomatal closure and immune defense in Arabidopsis. PLoS Biol. 11(3):e1001513

  9. de Zelicourt A, Al-Yousif M, Hirt H.(2013) Rhizosphere microbes as essential partners for plant stress tolerance. Mol Plant 6:242-5.

  10. Montillet, J-L., Hirt, H. (2013) New checkpoints in stomatal defense. Trends Plant Sci. 18(6):295-7.

  11. Evrard, A., Kumar, M., Lecourieux, D., Lucks, J., von Koskull-Doring, P., Hirt, H. (2013) Regulation of the heat stress response in Arabidopsis by MPK6-targeted phosphorylation of the heat stress factor HsfA2. Peer J 2;1:e59

  12. Garcia AV, Charrier A, Schikora A, Bigeard J, Pateyron S, de Tauzia-Moreau ML, Evrard A, Mithöfer A, Martin-Magniette ML, Virlogeux-Payant I, Hirt H. (2013) Salmonella enterica flagellin is recognized via FLS2 and activates PAMP-triggered immunity in Arabidopsis thaliana. Mol Plant. 7(4):657-74.

  13. Danquah A, de Zelicourt A, Colcombet J, Hirt H. (2013) The role of ABA and MAPK signaling pathways in plant abiotic stress responses. Biotechnol Adv. 32:40-52.

  14. Bigeard J, Pflieger D, Colcombet J, Gérard L, Mireau H, Hirt H. (2014) Protein Complexes Characterization in Arabidopsis thaliana by Tandem Affinity Purification Coupled to Mass Spectrometry Analysis. Methods Mol Biol. 1171:237-50.

  15. Hudik E, Berriri S, Hirt H, Colcombet J. (2014) Identification of Constitutively Active AtMPK6 Mutants Using a Functional Screen in Saccharomyces cerevisiae. Methods Mol Biol. 1171:67-77. 

  16. Bigeard J, Rayapuram N, Bonhomme L, Hirt H, Pflieger D. (2014) Proteomic and phosphoproteomic analyses of chromatin-associated proteins from Arabidopsis thaliana. Proteomics 14(19):2141-55.

  17.  Bigeard J, Rayapuram N, Pflieger D, Hirt H. (2014) Phosphorylation-dependent regulation of plant chromatin and chromatin-associated proteins. Proteomics 14(19):2127-40. 

  18.  García AV, Hirt H (2014) Salmonella enterica induces and subverts the plant immune system. Front. Microbiol. 5:141. 

  19.  Ovečka M, Takáč T, Komis G, Vadovič P, Bekešová S, Doskočilová A, Smékalová V, Luptovčiak I, Samajová O, Schweighofer A, Meskiene I, Jonak C, Křenek P, Lichtscheidl I, Skultéty L, Hirt H, Samaj J. (2014) Salt-induced subcellular kinase relocation and seedling susceptibility caused by overexpression of Medicago SIMKK in Arabidopsis. J. Exp. Bot. 65:2335-50. 

  20.  Rayapuram N, Bonhomme L, Bigeard J, Haddadou K, Przybylski C, Hirt H, Pflieger D. (2014) Identification of novel PAMP-triggered phosphorylation and dephosphorylation events in Arabidopsis thaliana by quantitative phosphoproteomic analysis. J Proteome Res.13:2137-51. 

  21. García AV, Hirt H. (2014) Salmonella enterica induces and subverts the plant immune system. Front Microbiol. 5:141.

  22.  Jégu T, Latrasse D, Delarue M, Hirt H, Domenichini S, Ariel F, Crespi M, Bergounioux C, Raynaud C, Benhamed M. (2014) The BAF60 subunit of the SWI/SNF chromatin-remodeling complex directly controls the formation of a gene loop at FLOWERING LOCUS C in Arabidopsis. Plant Cell 26:538-51. 

  23.  Garcia AV, Charrier A, Schikora A, Bigeard J, Pateyron S, de Tauzia-Moreau ML, Evrard A, Mithöfer A, Martin-Magniette ML, Virlogeux-Payant I, Hirt H (2014) Salmonella enterica flagellin is recognized via FLS2 and activates PAMP-triggered immunity in Arabidopsis thaliana. Mol Plant 7:657-74. 

  24.  Frei Dit Frey N, Garcia AV, Bigeard J, Zaag R, Bueso E, Garmier M, Pateyron S, de Tauzia-Moreau ML, Brunaud V, Balzergue S, Colcombet J, Aubourg S, Martin-Magniette ML, Hirt H. (2014) Functional analysis of Arabidopsis immune-related MAPKs uncovers a role for MPK3 as negative regulator of inducible defences. Genome Biol. 15(6):R87.

  25.  Zourelidou M, Absmanner B, Weller B, Barbosa IC, Willige BC, Fastner A, Streit V, Port SA, Colcombet J, de la Fuente van Bentem S, Hirt H, Kuster B, Schulze WX, Hammes UZ, Schwechheimer C. (2014) Auxin efflux by PIN-FORMED proteins is activated by two different protein kinases, D6 PROTEIN KINASE and PINOID. Elife e02860. 

  26.  Jégu T, Domenichini S, Blein T, Ariel F, Christ A, Kim SK, Crespi M, Boutet-Mercey S, Mouille G, Bourge M, Hirt H, Bergounioux C, Raynaud C, Benhamed M. (2015) A SWI/SNF Chromatin Remodelling Protein Controls Cytokinin Production through the Regulation of Chromatin Architecture. PLoS One. 10(10):e0138276.

  27. Boudsocq M, Danquah A, de Zélicourt A, Hirt H, Colcombet J. (2015) Plant MAPK cascades: Just rapid signaling modules? Plant Signal Behav. 10(9):e1062197.

  28. Bigeard J, Colcombet J, Hirt H.(2015) Signaling mechanisms in pattern-triggered immunity (PTI). Mol Plant. 8(4):521-39.

  29. Danquah A, de Zélicourt A, Boudsocq M, Neubauer J, Frei Dit Frey N, Leonhardt N, Pateyron S, Gwinner F, Tamby JP, Ortiz-Masia D, Marcote MJ, Hirt H, Colcombet J. (2015) Identification and characterization of an ABA-activated MAP kinase cascade in Arabidopsis thaliana. Plant J. 82(2):232-44.

  30. FF Lafi, A Bokhari, I Alam, VB Bajic, H Hirt, MM Saad (2016) Draft genome sequence of the plant growth-promoting Cupriavidus gilardii strain JZ4 isolated from the desert plant Tribulus terrestris. Genome Announcements 4 (4), e00678-16.

  31. Hirt H. (2016) Interview with Heribert Hirt.Trends Plant Sci. 2016 Jan;21(1):1-2

  32. M Ovečka, T Takáč, P Vyplelová, G Komis, S Bekešová, I Luptovčiak, I Luptovčiak, P Vadovič, O Šamajová, H Hirt, J Šamaj (2016) Overexpression of Medicago mitogen-activated protein kinase kinase SIMKK in Arabidopsis causes salt stress-induced subcellular relocation and enhanced salt sensitivity. New Biotechnology 33, S159-S160.

  33. Veluchamy A, Jégu T, Ariel F, Latrasse D, Mariappan KG, Kim SK, Crespi M, Hirt H, Bergounioux C, Raynaud C, Benhamed M. (2016) LHP1 Regulates H3K27me3 Spreading and Shapes the Three-Dimensional Conformation of the Arabidopsis Genome. PloS one 11 (7), e01589.

  34. H Hirt (2016) Aquaporins Link ROS Signaling to Plant Immunity.Plant Physiology 171 (3), 1540-154036.

  35.  de Zelicourt A, Colcombet J, Hirt H. (2016) The Role of MAPK Modules and ABA during Abiotic Stress Signaling. Trends in plant science Aug;21(8):677-85.

  36. JR Osman, A Zelicourt, T Bisseling, R Geurts, H Hirt, MS DuBow (2016) Bacterial Rhizosphere Biodiversity from Several Pioneer Desert Sand Plants Near Jizan, Saudi Arabia. The Open Conference Proceedings Journal 7 (1).

  37. Mahmood S, Daur I, Al-Solaimani SG, Ahmad S, Madkour MH, Yasir M, Hirt H, Ali S, Ali Z (2016) Plant Growth Promoting Rhizobacteria and Silicon Synergistically Enhance Salinity Tolerance of Mung Bean. Frontiers in Plant Science 7, 876.

  38. R Zhang, CPG Calixto, Y Marquez, P Venhuizen, NA Tzioutziou, W Guo, Mark Spensley, Nicolas Frei dit Frey, Heribert Hirt, Allan B James, Hugh G Nimmo, Andrea Barta, Maria Kalyna, John WS Brown. (2016) AtRTD2: A Reference Transcript Dataset for accurate quantification of alternative splicing and expression changes in Arabidopsis thaliana RNA-seq data. bioRxiv, 051938.

  39. Lafi FF, Ramirez-Prado JS, Alam I, Bajic VB, Hirt H, Saad MM.(2016) Draft Genome Sequence of Halomonas elongata Strain K4, an Endophytic Growth-Promoting Bacterium Enhancing Salinity Tolerance In Planta.Genome Announc. 2016 Nov 3;4(6).

  40. Jacob P, Hirt H, Bendahmane A. (2016)  The heat shock protein/chaperone network and multiple stress resistance.Plant Biotechnol J. 2016 Nov 10.

  41. Colcombet J, Sözen C, Hirt H. (2016) Convergence of Multiple MAP3Ks on MKK3 Identifies a Set of Novel Stress MAPK Modules. Front Plant Sci. Dec 22;7:1941.

  42. Chardin C, Schenk ST, Hirt H, Colcombet J, Krapp A (2017) Mitogen-activated protein kinases in nutrient signaling. Frontiers Plant Physiologie 260:101-108.

  43. Zhang R, Calixto CPG, Marquez Y, Venhuizen P, Tzioutziou NA, Guo W, Spensley M, Entizne JC, Lewandowska D, Ten Have S, Frei Dit Frey N, Hirt H, James AB, Nimmo HG, Barta A, Kalyna M, Brown JWS (2017) A high quality Arabidopsis transcriptome for accurate transcript-level analysis of alternative splicing. Nucleic Acids Res.45(9):5061-5073.

  44. Genot B, Lang J, Berriri S, Garmier M, Gilard F, Pateyron S, Haustraete K, Van Der Straeten D, Hirt H, Colcombet J (2017) Constitutively Active Arabidopsis MAP Kinase 3 Triggers Defense Responses Involving Salicylic Acid and SUMM2 Resistance Protein. Plant Physiol. 174(2):1238-1249.

  45. Jégu T, Veluchamy A, Ramirez-Prado JS, Rizzi-Paillet C, Perez M, Lhomme A, Latrasse D, Coleno E, Vicaire S, Legras S, Jost B, Rougée M, Barneche F, Bergounioux C, Crespi M, Mahfouz MM, Hirt H, Raynaud C, Benhamed M (2017) The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility. Genome Biol. 18(1):114.

  46. Latrasse D, Jégu T, Li H, de Zelicourt A, Raynaud C, Legras S, Gust A, Samajova O, Veluchamy A, Rayapuram N, Ramirez-Prado JS, Kulikova O, Colcombet J, Bigeard J, Genot B, Bisseling T, Benhamed M, Hirt H. (2017) MAPK-triggered chromatin reprogramming by histone deacetylase in plant innate immunity. Genome Biol. 18(1):131.

  47. Lang J, Genot B, Hirt H, Colcombet J (2017) Constitutive activity of the Arabidopsis MAP Kinase 3 confers resistance to Pseudomonas syringae and drives robust immune responses. Plant Signal Behav. 12(8):e1356533.

  48. Li H, Torres-Garcia J, Latrasse D, Benhamed M, Schilderink S, Zhou W, Kulikova O, Hirt H, Bisseling T. (2017) Plant-Specific Histone Deacetylases HDT1/2 Regulate GIBBERELLIN 2-OXIDASE2 Expression to Control Arabidopsis Root Meristem Cell Number. Plant Cell. 29(9):2183-2196. 

  49. Andrés-Barrao C, Lafi FF, Alam I, de Zélicourt A, Eida AA, Bokhari A, Alzubaidy H, Bajic VB, Hirt H, Saad MM. (2017) Complete Genome Sequence Analysis of Enterobacter sp. SA187, a Plant Multi-Stress Tolerance Promoting Endophytic Bacterium.Front Microbiol. 8:2023

  50. Rayapuram N, Bigeard J, Alhoraibi H, Bonhomme L, Hesse AM, Vinh J, Hirt H, Pflieger D. (2018) Quantitative Phosphoproteomic Analysis Reveals Shared and Specific Targets of Arabidopsis Mitogen-Activated Protein Kinases (MAPKs) MPK3, MPK4, and MPK6. Mol Cell Proteomics. 17(1):61-80.

  51. de Zélicourt A, Synek L, Saad MM, Alzubaidy H, Jalal R, Xie Y, Andrés-Barrao C, Rolli E, Guerard F, Mariappan KG, Daur I, Colcombet J, Benhamed M, Depaepe T, Van Der Straeten D, Hirt H. (2018) Ethylene induced plant stress tolerance by Enterobacter sp. SA187 is mediated by 2-keto-4-methylthiobutyric acid production. PLoS Genet. 14(3):e1007273. 

  52. Bang C, Dagan T, Deines P, Dubilier N, Duschl WJ, Fraune S, Hentschel U, Hirt H, Hülter N, Lachnit T, Picazo D, Pita L, Pogoreutz C, Rädecker N, Saad MM, Schmitz RA, Schulenburg H, Voolstra CR, Weiland-Bräuer N, Ziegler M, Bosch TCG. (2018) Metaorganisms in extreme environments: do microbes play a role in organismal adaptation? Zoology 127:1-19. 

  53. Ramirez-Prado JS, Piquerez SJM, Bendahmane A, Hirt H, Raynaud C, Benhamed M. (2018) Modify the Histone to Win the Battle: Chromatin Dynamics in Plant-Pathogen Interactions. Front Plant Sci. 9:355.

  54. Daur I, Saad MM, Eida AA, Ahmad S, Shah ZH, Ihsan MZ, Muhammad Y, Sohrab SS, Hirt H (2018) Boosting Alfalfa (Medicago sativa L.) Production With Rhizobacteria From Various Plants in Saudi Arabia. Front Microbiol. 9:477. 

  55. Bigeard J, Hirt H. (2018) Nuclear Signaling of Plant MAPKs. Front Plant Sci. 9:469. 

  56. Othoum G, Bougouffa S, Razali R, Bokhari A, Alamoudi S, Antunes A, Gao X, Hoehndorf R, Arold ST, Gojobori T, Hirt H, Mijakovic I, Bajic VB, Lafi FF, Essack M. (2018) In silico exploration of Red Sea Bacillus genomes for natural product biosynthetic gene clusters. BMC Genomics. 19(1):382. 

  57. Ramirez-Prado JS, Abulfaraj AA, Rayapuram N, Benhamed M, Hirt H. (2018) Plant Immunity: From Signaling to Epigenetic Control of Defense. Trends Plant Sci. 23(9):833-844.

  58. Alhoraibi H, Bigeard J, Rayapuram N, Colcombet J, Hirt H. (2018) Plant Immunity: The MTI-ETI Model and Beyond. Curr Issues Mol Biol. 30:39-58.

  59. Abulfaraj, AA, Mariappan, K, Bigeard, J, Manickam, P, Blilou, I, Guo, X, Al-Babili, S, Pflieger, D, Hirt H, Rayapuram N (2018) The Arabidopsis homolog of human G3BP1 is a key regulator of stomatal and apoplastic immunity. Life Sci Alliance 1(2):e201800046.

  60. Eida AA, Ziegler M, Lafi FF, Michell CT, Voolstra CR, Hirt H, Saad MM (2018) Desert plant bacteria reveal host influence and beneficial plant growth properties.PLoS One 13(12):e0208223

  61. Saad MM, de Zelicourt A, Rolli E, Synek L, Hirt H (2018). Quantification of Root Colonizing Bacteria. Bio-protocol Bio101: e2927.

  62. Völz R, Kim SK, Mi J, Mariappan KG, Guo X, Bigeard J, Alejandro S, Pflieger D, Rayapuram N, Al-Babili S, Hirt H. (2018) The Trihelix transcription factor GT2-like 1 (GTL1) promotes salicylic acid metabolism, and regulates bacterial-triggered immunity. PLoS Genet. 14 (10):e1007708.

  63. AA Eida, HS Alzubaidy, A de Zélicourt, L Synek, Hirt H and Saad, MM. (2019) Phylogenetically diverse endophytic bacteria from desert plants induce transcriptional changes of tissue-specific ion transporters and salinity stress in Arabidopsis thaliana. Plant Science, 280:228-240.

  64. Völz R, Kim SK, Mi J, Rawat AA, Veluchamy A, Mariappan KG, Rayapuram N, Daviere JM, Achard P, Blilou I, Al-Babili S, Benhamed M, Hirt H. (2019) INDETERMINATE-DOMAIN 4 (IDD4) coordinates immune responses with plant-growth in Arabidopsis thaliana. PLoS Pathog. 15(1):e1007499.

  65. Beaugelin I, Chevalier A, D'Alessandro S, Ksas B, Novák O, Strnad M, Forzani C, Hirt H, Havaux M, Monnet F. (2019) OXI1 and DAD regulate light-induced cell death antagonistically through jasmonate and salicylate levels. Plant Physiol. pii: pp.00353.2019.

  66. Völz R, Kim SK, Mi J, Mariappan KG, Siodmak A, Al-Babili S, Hirt H. (2019) A chimeric IDD4 repressor constitutively induces immunity in Arabidopsis via the modulation of salicylic- and jasmonic acid homeostasis. Plant Cell Physiol. pii: pcz057.


  1. Meskiene, I., Jonak, C., and Hirt, H. (2000) Regulation of mitogen-activated protein kinase (MAPK). R37248 (A 1880/2000)

  2. Jonak, C., and Hirt, H. (2001) Protein with Kinase Activity. R38340 

  3. De Zelicourt, Saad, M. and Hirt, H (2016) Compositions And Methods For Providing Plants With Tolerance to Abiotic Stress Condition. US No.  62/281,404

  4. H Hirt, A de Zelicourt, M Saad Compositions and methods for increasing salt tolerance in plants. (2019) US Patent App. 16/048,142

Articles in books, monographs, etc. 

  1. Eberhardt, P. Cattini, H. Hirt, T. Anderson, L. Peritz, J.  Baxter, P. Mellon, R. Isaacs, E. Slater and A. Barta (1987). Human growth hormone genes: structure, evolution, expression and hormonal regulation. In: Selected Topics in Mol. Endocrin., 58-67. 

  2. Wiche, R. Foisner, H. Herrmann, H. Hirt and G. Weizer. (1987) Plectin and High Mol Weight MAPs: Versatile connecting Links of  the Cytoskeleton. In: The Cytoskeleton in Cell Differentiation and Development, ICSU symp. ser. vol. 8. (Macchioni R. and Arrechaga J., eds.), IRL Press, Oxford, 107-117.

  3. Meskiene, W.C. Yang, C. deBlank, L. Bögre, K. Zwerger, M. Brandstötter, M. Mattauch, T. Bisseling, and H. Hirt (1997) Cell cycle regulation and nodule development. In: Biological fixation of nitrogen for ecology and sustainable agriculture (H. Bothe, ed.) NATO ASI series, Springer Verlag, Vol. G39, 63-65.

  4. Kondorosi, E., H. Trinh, F. Roudier, F. Foucher, D. Vaubert, A. Cebolla, A. Lodeiro, A. Feher, Z. Keleman, J. Györgyey, P. Mergaert, A. Kereszt, D. Dudits, H. Hirt, and A. Kondorosi (1997) Nod factor-induced cell cycle activation in root cortical cells. In: Biological Nitrogen Fixation for the 21st Century (eds. C. Elmerich, A. Kondorosi, W.E: Newton) Kluwer Acad. Publ. pp. 189-192. 

  5. Hirt, L. Bögre, I. Meskiene, M. Dahl, K. Zwerger, and E. Heberle-Bors (1998) Functional isolation and selection of plant cell cycle genes in yeast. In: Molecular and Cell Biology of the Plant Cell Cycle (D. Dudits, D. Francis, and D. Inze, eds.) Portland Press Ltd, London, 129-143.

  6. Hirt, H. (2000) MAP kinases in plant signal transduction. Series: Results and Problems in Cell Differentiation (H. Hirt, ed.) Springer, Heidelberg, Vol 27, 1-9.

  7.  Hirt, H., and Scheel, D. (2000) Receptor-mediated MAP kinase activation in plant defense. In: MAP kinases in plant signal transduction. Series: Results and Problems in Cell Differentiation (H. Hirt, ed.) Springer, Heidelberg, Vol 27, 85-92.

  8. Jonak, C. Kiegerl, S., Ligterink, W., Siligan, C., Baudouin, E. Beyerly, J., Cardinale, F., Hausl, C., Zwerger, K., Meskiene, I., and Hirt, H. (2000) MAP kinases in plant signal transduction : Versatile tools for signaling stress, cell cycle, and more. J.H. Cherry et al. (eds.) Plant Tolerance to Abiotic Stresses: Role of genetic Engineering, Kluwer Academic Publishers, 67-79.

  9. Scheel, D., Blume, B., Brunner, F., Fellbrich, G., Dalbøge, H., Hirt, H., Kauppinen, S., Kroj, T., Ligterink, W., Nürnberger, T., Tschöpe, M., Zinecker, H., zur Nieden, U. (2000): Receptor-mediated signal transduction in plant defense. In: Biology of Plant-Microbe Interactions, Vol. 2 (de Wit, P.J.G.M., Bisseling, T., Stiekema, W.J., eds.), International Society for Molecular Plant-Microbe Interactions, St. Paul, U.S.A., pp. 131-135.

  10. Hirt H. (2004) Plant responses to abiotic stress. In: Topics in Curr. Genetics Vol 4 (H. Hirt and K. Shinozaki, eds.), Springer Verlag Berlin-Heidelberg, 1-9

  11. Ovecka, M., Lichtscheidl, I.K., Baluska, F., Šamaj, J., Volkmann, D., and Hirt, H. (2008) Regulation Of Root Hair Tip Growth: Can Mitogen-Activated Protein Kinases Be Taken Into Account? (Blume, Y.B., Baird, W.V., Yemets, A.I. and Breviario D.) The Plant Cytoskeleton: a Key Tool for Agro-Biotechnology NATO ASI series, Springer Verlag, Vol. , 91-108.

  12. Van Bentem, S., de la Fuente, A., and Hirt, H. (2009) Integrative approaches to elucidate and analyse protein interaction and signalling networks. (H. Hirt, ed.) Plant stress biology: from genomics to systems biology, Wiley, pp. 227-245.

  13. Schikora, A., Garcia, A.V., Charrier, A. and Hirt, H. (2012) Infection of Plants by the Human Pathogen Salmonella Typhimurium: Challenges and New Insights. G. Witzany and F. Baluska (eds.), Biocommunication of Plants, Signaling and Communication in Plants 14, 349-359. Interview with Heribert Hirt

  14. H Hirt (2016) Trends in plant science 21 (1), 1-2.

  15. Lafi FF, Alam I, Geurts R, Bisseling T, Bajic VB, Hirt H, Saad MM. (2016)  Draft Genome Sequence of the Phosphate-Solubilizing Bacterium Pseudomonas argentinensis Strain SA190 Isolated from the Desert Plant Indigofera argentea.Genome Announc. 2016 Dec 22;4(6). 

  16. Lafi FF, Ramirez-Prado JS, Alam I, Bajic VB, Hirt H, Saad MM. (2017) Draft Genome Sequence of Plant Growth-Promoting Micrococcus luteus Strain K39 Isolated from Cyperus conglomeratus in Saudi Arabia. Genome Announc. 5(4). pii: e01520-16.

  17. Lafi FF, AlBladi ML, Salem NM, Al-Banna L, Alam I, Bajic VB, Hirt H, Saad MM.(2017) Draft Genome Sequence of the Plant Growth-Promoting Pseudomonas punonensis Strain D1-6 Isolated from the Desert Plant Erodium hirtum in Jordan. Genome Announc. 2017 Jan 12;5(2). pii: e01437-16. 

  18. Lafi FF, Alam I, Geurts R., Bisseling T, Bajic VB, Hirt H, Saad MM. (2017)  Draft Genome Sequence of the Plant Growth-Promoting Rhizobacterium Acinetobacter radioresistens Strain SA188 Isolated from the Desert Plant Indigofera argentea Genome Announc 5(9). pii: e01708-16.

  19. Lafi FF, Alam I, Geurts R., Bisseling T, Bajic VB, Hirt H, Saad MM (2017) Draft Genome Sequence of Ochrobactrum intermedium Strain SA148, A Plant Growth-Promoting Desert Rhizobacterium Genome Announc 5(9). pii: e01707-16.

  20. Lafi FF, de Zelicourt, Alam I, Geurts R., Bisseling T, Bajic VB, Hirt H, Saad MM (2017) Draft Genome Sequence of Endophytic Bacterium Enterobacter sp. SA187 Isolated from Desert Plant Indigofera argentea 5(7). pii: e01638-16.

  21. Eida AA, Hirt H, Saad MM (2017) Challenges Faced in Field Application of Phosphate-Solubilizing Bacteria, in Rhizotrophs: Plant Growth Promotion to Bioremediation, S. Mehnaz, Editor, Springer Singapore: Singapore. p. 125-143.

  22. C Jonak, H Hirt (2018) Cytoplasmatic Protein Kinases in Signal Transduction. Annual Plant Reviews, 249-268.

Editor of Books

  1. Hirt, H. (2000) MAP kinases in plant signal transduction. Series: Results and Problems in Cell Differentiation Springer, Heidelberg, Vol 27.

  2. Hirt H. and Shinozaki, K. (2004) Plant responses to abiotic stress. In: Topics in Curr. Genetics Vol 4, Springer Verlag Berlin-Heidelberg, 

  3. Hirt, H.(2009) Plant stress biology: From genomics to systems biology, Wiley.